What Is Eye Lymphoma?
In contrast to other systemic lymphomas, which usually involve the retina and iris (the colored portion of the eye), primary intraocular lymphoma (PIOL) involves the retina, vitreous and optic nerve. Eighty percent of cases involve both eyes; many people with PIOL will develop lymphoma within the part of the brain called the cerebrum.
The two main types of lymphoma are Hodgkin’s disease and non-Hodgkin’s lymphoma. Primary intraocular lymphoma is almost always a non-Hodgkin’s B cell lymphoma. Most people with primary intraocular lymphoma are elderly or have immune system diseases such as AIDS (acquired immunodeficiency syndrome). Primary intraocular lymphoma often occurs with lymphoma of the brain, called primary central nervous system lymphoma (PCNSL).