Part A reproduced from External Disease and Cornea: A Multimedia Collection. San Francisco: American Academy of Ophthalmology; 2000. Parts B and C courtesy of George J. Harocopos, MD.
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Ocular Pathology/Oncology
Fuchs endothelial corneal dystrophy. A, Slit-lamp illumination of the cornea shows “beaten bronze” appearance of Descemet membrane (arrow). B, Corneal button from PK shows endothelial cell loss, with few surviving endothelial cells (E). Numerous guttae are seen in Descemet membrane (arrows). The result of endothelial decompensation is diffuse stromal edema (note loss of interlamellar clefts) and epithelial bulla (asterisk). C, Specimen from Descemet membrane–stripping endothelial keratoplasty (DSEK) shows few endothelial cells (E) and numerous guttae (arrows).