By Richard T. Cornwell, CRA, ROUB, COA, Columbia Eye Clinic, Columbia, S.C. Edited by Richard E. Hackel, MA, CRA, FOPS. Photo Credits: Richard T. Cornwell, CRA, ROUB, COA, Columbia Eye Clinic, Columbia, S.C.
This patient was referred to us for a retina consultation. Her history included systemic lupus erythematosus and treatment with hydroxychloroquine and chloroquine. Interestingly, she had discontinued the hydroxychloroquine four to five years ago and the chloroquine approximately one year ago. Her best corrected visual acuity was 20/50 in each eye but with significant color vision loss (1/11 color plates correct). Fluorescein angiography showed bilateral bulls-eye lesions in the retinal pigment epithelium. Optical coherence tomography indicated significant thinning of the fovea. The color photographs demonstrated small hyperreflective entities that are assumed to be residual deposits of chloroquine in the retinal pigment epithelium. ___________________________
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