A 54-year-old woman was referred to us for evaluation of an iris lesion that had been slowly enlarging for nine years. She was completely asymptomatic.

Anterior segment examination revealed an elevated, amelanotic iris lesion that measured 4 x 2.3 mm and appeared gelatinous and highly vascularized. It did not extend to involve the angle, as viewed on gonioscopy. The lesion caused peaking of the pupil and ectropion uveae. The remainder of the examination was normal.

A fluorescein angiogram revealed prominent vascularity of the iris lesion. An anterior segment B-scan showed that the mass was limited to the iris stroma and did not distort the iris pigment epithelium; there was no involvement of the ciliary body. An incisional biopsy confirmed the diagnosis of amelanotic iris nevus.