Neurofibromatosis Type I: Lisch Nodules
The are melanotic hamartomas present in over 90% of patients with Neurofibromatosis Type 1 after age 6. They are hard to recognize without a biomicroscope and do not affect vision.
Other ophthalmic complications
Optic nerve and are found in 15% of Neurofibromatosis Type 1 patients. These are very indolent neoplasms that may not grow. In 50% of cases, they impair vision.
Treatment for growing optic pathway astrocytomas is radiation or chemotherapy. Both methods may halt growth, but reversal of vision loss is rare.
Neurofibromatosis Type 1 patients also get plexiform neurofibromas on the eyelids and glaucoma. When eyelid masses are present, 50% of patients have glaucoma.