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Amiodarone: Keratopathy

Keratopathy

You are looking at whorl-like opacities in the corneal epithelium. They appear in nearly 100% of patients treated for more than six months with amiodarone (brand name Cordarone), an anti-arrhythmic.

Although the corneal abnormality is impressive, fewer than 10% of patients are bothered by it —complaining of blurred vision or haloes. The whorls disappear within months of discontinuing the drug. There is controversy about whether this drug causes optic nerve damage.

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