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Prednisone: Cataract


This patient has developed an opacification of the posterior lens cortex, just beneath the surface of the posterior lens capsule ("posterior subcapsular cataract"). It is caused by chronic treatment with prednisone, the agent most likely to cause cataract.

The development of cataract is related to the cumulative dose of prednisone; 25% of patients who use 15 mg/day for 1 year or more will get cataracts that interfere enough with vision to require surgical removal.

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