New Optic Neuritis Biomarkers

In this 1-Minute Video, Dr. John Chen discusses 2 new biomarkers for optic neuritis. The antibody against aquaporin 4 (AQP4-IgG) is a marker and pathologic cause for neuromyelitis optic (NMO). Meanwhile, the antibody against myelin oligodendrocyte glycoprotein (MOG-IgG) indicates a unique demyelinating disorder that is separate from both multiple sclerosis or NMO. MOG optic neuritis is often bilateral, recurrent and associated with optic disc edema. Dr. Chen recommends evaluating patients for these antibodies because NMO or MOG optic neuritis requires different treatment than multiple sclerosis.

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