This video describes the technique of implantation of an epidescemetic keratoprosthesis with the assistance of a femtosecond laser, an easy technique with minimal complications. A deeper outer diameter cut is made followed by a shallower cut in the interior corneal dissection. The cut is set at 100 µm from the Descemet membrane and then the stroma dissected manually with a crescent knife. Anterior segment optical coherence tomography pachymetry is used to plan a good depth of the femtosecond cuts. The optical zone of 3.5 mm must be placed in the visual axis.