In this presentation from AAO 2015, Dr. Sadeer B. Hannush discusses a case of neurotrophic keratitis with corneal ulceration in a 79-year-old man with a history of herpes simplex in the affected eye. The patient was successfully managed with a maintenance course of 400 mg oral acyclovir, closure of the puncta, a bandage contact lens, topical lubricants and antibiotics, and protective eyewear. Complete re-epithelialization was achieved after 2 weeks.