By Savari Desai; Santosh G Honavar MD; Gangadhar Jalli; Shobha Mocherla; Rajkumar Mendhikar
    Ocular Pathology/Oncology

    Ocular surface squamous neoplasia encompasses dysplasia, carcinoma-in-situ, and invasive carcinoma of the conjunctiva and corneal epithelium. The spectrum of clinical manifestations of this common clinical condition is diverse. Although the management modalities may include topical chemotherapy, immunotherapy, and radiotherapy, complete surgical excision is the primary treatment of choice. The surgical protocol is comprised of tumor excision with clear margins by the "minimal manipulation technique", alcohol keratoepitheliectomy of the corneal epithelial component, and excision edge cryotherapy. Fewer than 5% of tumors recur with protocol-based management. In this video, we highlight the spectrum of clinical manifestations and the nuances of the surgical technique