APR 01, 2020
Ocular Surface Squamous Neoplasia With Concomitant Simple Limbal Epithelial Transplantation
AAO 2019 Video Program
Ocular Pathology/Oncology
Complete tumor excision with 4-mm wide margins remains the mainstay of treatment for ocular surface squamous neoplasia (OSSN). Large OSSNs involving 4 to 6 clock hours involve extensive corneoscleral limbal dissection, resulting in limbal stem cell deficiency (LSCD) and surface instability. Simple limbal epithelial transplantation (SLET) is a novel technique where limbal stem cells are harvested from the normal corneoscleral limbus of the patient. SLET technique has been extensively used for LSCD secondary to ocular surface burns and has shown satisfactory results. This video describes in simple steps the technique of harvesting limbal stem cells by peripheral lamellar dissection from the uninvolved corneoscleral limbus and transplanting them onto the corneal surface of the involved eye after complete tumor excision.