OSSN Management Options: Not One Size Fits All

Ocular surface squamous neoplasia (OSSN) is an encompassing term for precancerous and cancerous epithelial lesions of the conjunctiva and cornea, including the spectrum of dysplasia, carcinoma in situ (CIN), and invasive tumor. There are no consistent clinical criteria for distinguishing CIN from invasive OSSN. Diagnostic imaging is an important tool in the diagnosis and management of OSSN. The management ranges from topical immunomodulation therapy to a radical surgery like exenteration, depending on the presentation of OSSN. Careful management planning and optimal use of treatment options, including multimodal treatment, can result in minimal recurrence and complications. Compliance to therapy and follow-up are the key to remission of disease.