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    By Donald Tan MD FRCS FRCOphth; Jodhbir S Mehta MBBCH BS
    Cornea/External Disease

    The EndoGlide is a new disposable donor inserter for Descemet-stripping automated endothelial keratoplasty (DSAEK), designed for simple insertion with minimal donor damage through a 4–4.5mm wound. Using the glide pull-through concept, the donor is double-coiled into a clear glide chamber, which is inserted through a 4–4.5mm wound, and the donor is pulled in with forceps. We first performed eye bank trypan blue studies, which revealed a mean 5% endothelial cell loss with the device. We then performed DSAEK in 4 patients with the EndoGlide. All cases were successful, with no donor dislocation or graft failure. Postoperative endothelial cell counts for the first 2 cases revealed 13.8% cell loss at 1 month (1st case), and 9.1% and 13.4% cell loss at 1 week and 1 month (2nd case). Following these encouraging results, we have initiated a 100-patient clinical trial to further assess safety and efficacy of the EndoGlide.