Aqueous Outflow and Glaucoma Drug Mechanisms of Action

Aqueous humor outflow occurs through two pathways, the trabecular—or conventional—and uveoscleral pathways. The conventional pathway is responsible for approximately 85% of aqueous outflow. This simple video model shows how outflow facility changes in the case of open-angle glaucoma, as well as the mechanism of action of glaucoma drugs that impact either trabecular or uveoscleral outflow to help lower intraocular pressure.