Hyperosmolar drugs are used to decrease corneal and epithelial edema. One such drug is sodium chloride, which is available without a prescription in a 2% or 5% solution or as an ointment. These products are used to treat corneal edema from Fuchs endothelial corneal dystrophy, other causes of endothelial dysfunction, postoperative prolonged edema, and recurrent erosion syndrome.
Excerpted from BCSC 2020-2021 series: Section 2 - Fundamentals and Principles of Ophthalmology. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.