Vitreous Opacification and Vitritis
Vitreous membranes in chronic cases not responding to steroid treatment to a degree that vision is affected may occur in uveitis. Vitrectomy in eyes with quiet inflammation may improve visual acuity in these cases, with 1 review of studies on pars plana vitrectomy in uveitis showing visual acuity improved in 68%. A standard small (25- or 23-gauge) 3-port pars plana vitrectomy is the preferred technique, with a few minor variations (see BCSC Section 12, Retina and Vitreous).
Davis JL, Miller DM, Ruiz P. Diagnostic testing of vitrectomy specimens. Am J Ophthalmol. 2005;140(5):822–829.
Manku H, McCluskey P. Diagnostic vitreous biopsy in patients with uveitis: a useful investigation? Clin Exp Ophthalmol. 2005;33(6):604–610.
Excerpted from BCSC 2020-2021 series: Section 9 - Uveitis and Ocular Inflammation. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.