Chronic Renal Disease
Aggressive treatment, often with 3 or more drugs, may be necessary to achieve a BP goal of less than 130/80 mm Hg and to prevent deterioration of renal function and cardiovascular complications in hypertensive patients with chronic renal disease. ACE inhibitors and ARBs favorably alter the progression of diabetic and nondiabetic nephropathy. However, as the GFR nears 20 mL/min, less aggressive treatment may be appropriate, particularly in patients with renin-angiotensin-aldosterone system suppression.
Excerpted from BCSC 2020-2021 series: Section 1 - Update on General Medicine. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.