Unique regional immune responses in the eye influence ocular pathology.
In the context of immune privilege of the eye, several immunoregulatory mechanisms have evolved to modulate the intraocular immune environment.
Anterior chamber–associated immune deviation (ACAID) is a recognized facet of ocular immune privilege.
Understanding these ocular immune responses has been valuable to the progress of corneal transplantation, retinal gene therapy, and other developing cell-based therapies.
Excerpted from BCSC 2020-2021 series: Section 9 - Uveitis and Ocular Inflammation. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.