The orbit is the most common site of ocular metastasis in children, in contrast to adults, in whom the uvea is the most frequent site.
Neuroblastoma is the most frequent source of orbital metastasis in childhood. This disorder is discussed in Chapter 28.
Ewing sarcoma is composed of small round cells and usually originates in the long bones of the extremities or in the axial skeleton. Among solid tumors, Ewing sarcoma is the second most frequent source of orbital metastasis. Treatment regimens involving surgery, radiation, and chemotherapy allow long-term survival in many patients with disseminated disease.
Excerpted from BCSC 2020-2021 series: Section 10 - Glaucoma. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.