Necrotizing Herpetic Retinitis
Patients with AIDS may develop necrotizing herpetic retinitis, which appears to manifest as a spectrum of disease; the severity is directly proportional to the level of immunologic compromise. Patients may develop typical acute retinal necrosis or progressive outer retinal necrosis (PORN; see Chapter 11). In its early stages, PORN may be difficult to differentiate from peripheral CMV retinitis (Fig 15-2).
Kim SJ, Equi R, Belair ML, Fine HF, Dunn JP. Long-term preservation of vision in progressive outer retinal necrosis treated with combination antiviral drugs and highly active antiretroviral therapy. Ocul Immunol Inflamm. 2007;15(6):425–427.
Excerpted from BCSC 2020-2021 series: Section 9 - Uveitis and Ocular Inflammation. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.