The vitreous represents up to 80% of the volume of the eye.
Vitreous liquefaction has been associated with loss of vitreous ascorbate and the development of posterior vitreous detachment.
Pars plana vitrectomy increases the diffusion of oxygen in the posterior segment of the eye. The resultant increase in oxidative stress has been implicated in the acceleration of cataract formation after vitrectomy.
Excerpted from BCSC 2020-2021 series: Section 2 - Fundamentals and Principles of Ophthalmology. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.