Microphthalmia refers to a smaller than average eye with associated developmental defects (eg, persistent fetal vasculature). Colobomas and scleral defects with cystic outpouchings of intraocular contents (microphthalmia with cyst) are also common, because of failure of the fetal fissure to close completely.
See BCSC Section 6, Pediatric Ophthalmology and Strabismus, and Section 7, Oculofacial Plastic and Orbital Surgery, for additional discussion of microphthalmia.
Excerpted from BCSC 2020-2021 series: Section 4 - Ophthalmic Pathology and Intraocular Tumors. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.