Photophobia occurs most frequently as a result of ocular inflammatory disorders, including keratitis and uveitis (particularly iritis), and less commonly from chorioretinitis, retinal degenerative disorders, and lesions along the course of the anterior or retrochiasmal visual pathway. Photophobia may also occur because of meningeal irritation (eg, meningitis, subarachnoid hemorrhage) or migraine and is commonly reported by patients with traumatic brain injury.
Katz BJ, Digre KB. Diagnosis, pathophysiology, and treatment of photophobia. Surv Ophthalmol. 2016; 61(4): 466–477.
Excerpted from BCSC 2020-2021 series: Section 5 - Neuro-Ophthalmology. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.