Primary tumors of the angle structures are not known to occur. Melanocytic nevi and melanomas that arise in the iris or extend to the iris from the ciliary body may invade or obstruct the trabecular meshwork (Fig 7-16). See also Chapter 17. In addition, pigment elaborated from melanomas and melanocytomas may be shed into the trabecular meshwork, leading to secondary glaucoma (melanomalytic glaucoma) (see Fig 7-14). Occasionally, epibulbar tumors such as conjunctival carcinoma can invade the eye through the limbus, resulting in trabecular outflow obstruction and glaucoma. See the section Neoplasia in Chapter 5 for further discussion.
Excerpted from BCSC 2020-2021 series: Section 4 - Ophthalmic Pathology and Intraocular Tumors. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.