A variety of developmental anomalies can occur in the vitreous. These range from Mittendorf dot and Bergmeister papilla to persistent fetal vasculature.
Inflammation in the vitreous body can be a sign of potentially sight-threatening processes.
Posterior vitreous detachment plays an important role in the development of many retinal conditions.
Primary intraocular lymphoma generally presents as cells in the vitreous and may be a challenging diagnosis to make with routine cytology. This diagnosis usually requires special pathologic techniques, communication between the surgeon and pathologist regarding specimen handling, and a pathologist experienced with vitreous pathology.
Excerpted from BCSC 2020-2021 series: Section 4 - Ophthalmic Pathology and Intraocular Tumors. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.