A Kayser-Fleischer ring is found not only in Wilson disease but also in primary biliary cirrhosis, chronic active hepatitis, and exogenous chalcosis. It should not be confused with a Fleischer ring, an iron ring seen in keratoconus.
Crystals in the cornea are often related to amyloid deposition but may also be related to cystinosis and dysproteinemia.
Patients with diabetes mellitus may have problems with epithelial healing after debridement and are at risk for recurrent corneal erosion.
The differential diagnosis for prominent corneal nerves includes multiple endocrine neoplasia.
Excerpted from BCSC 2020-2021 series: Section 10 - Glaucoma. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.