Neurogenic and Smooth-Muscle Tumors
Subconjunctival peripheral nerve sheath tumors such as neurofibromas, schwannomas, and neuromas have been reported, especially in multiple endocrine neoplasia (MEN). A neurofibroma of the conjunctiva or eyelid is almost always a manifestation of neurofibromatosis, an autosomal dominant phakomatosis (see BCSC Section 6, Pediatric Ophthalmology and Strabismus). A neurilemoma is a very rare tumor of the conjunctiva that originates from Schwann cells of a peripheral nerve sheath. A leiomyosarcoma is a very rare limbal lesion with the potential for orbital invasion.
Excerpted from BCSC 2020-2021 series: Section 10 - Glaucoma. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.