2020–2021 BCSC Basic and Clinical Science Course™
6 Pediatric Ophthalmology and Strabismus
Part II: Pediatric Ophthalmology
Chapter 24: Uveitis in the Pediatric Age Group
Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a primary vasculitis mediated by immunoglobulin (Ig) A affecting children younger than 5 years. Abnormalities include fever, conjunctival injection, mucous membrane changes, extremity changes involving the skin, rash, and cervical lymphadenopathy. The most significant complication of Kawasaki disease is coronary artery aneurysm, which occurs in 15%–25% of untreated children. Treatment with aspirin and intravenous IgG reduces the incidence of coronary artery aneurysm formation. After conjunctivitis, a generally self-limited anterior uveitis during the acute phase of the illness is the second most common ocular finding, occurring in approximately 10% of cases.
Excerpted from BCSC 2020-2021 series: Section 10 - Glaucoma. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.