The optic nerve is part of the CNS, and like the brain and spinal cord, it is vulnerable to traumatic injury. Injury to the optic nerve may result in irreversible axonal degeneration and vision loss. There is ongoing research to evaluate and modulate the innate immune response to injury, as well as to promote axonal regeneration and remyelination, but effective therapies for optic nerve injury are not currently available.
Excerpted from BCSC 2020-2021 series: Section 4 - Ophthalmic Pathology and Intraocular Tumors. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.