• By James M. Rynerson, MD
    This Current Insight proposes that blepharitis and dry eye disease are actually one simple disease process caused by biofilm.
    Current Insight
    By
    This Current Insight takes an in-depth look at the rising rates of postkeratoplasty fungal infections.
    Current Insight
    By
    This review describes the evolution of corneal cross-linking, and examines its future in the treatment of corneal disease.
    Current Insight
    By
    New research shows dry eye is a complex disease process, prompting calls to redefine this disease.
    Current Insight
    By Terry Kim, MD; Jay J. Meyer, MD, MPH
    Superficial keratectomy can be used to treat the vast majority of Salzmann’s nodules, with proper instrumentation, surgical technique and postoperative management reducing the risk of recurrence.
    Current Insight
    By Frederick (Rick) W. Fraunfelder, MD, MBA
    Conjunctivochalasis and lymphangiectasia are similar-appearing conjunctival conditions that can be successfully treated with liquid nitrogen cryotherapy. This therapy probably works for both conditions by tacking down the conjunctiva to the underlying globe through a cryogen…
    Current Insight
    By Sonia H. Yoo, MD; Victoria Chang, BS
    Descemet's stripping automated endothelial keratoplasty (DSAEK) is becoming the treatment of choice for corneal endothelial failure due to its better preservation of the globe's integrity, typically faster visual rehabilitation and more predictable visual outcomes compared w…
    Current Insight
    By Ayad A. Farjo, MD; Qais A. Farjo, MD
    Current therapeutic modalities have been helpful in treating many patients with ocular surface disease and dysfunctional tear syndrome. But there remains a subset of patients who continue to have signs and symptoms in spite of aggressive lubricant and anti-inflammatory thera…
    Current Insight
    By Aaleya F. Koreishi, MD; Richard M. Awdeh, MD
    One of the most dreaded complications of penetrating keratoplasty is postoperative endophthalmitis, the incidence of which has been reported to be approximately 0.2% to 0.77%.1 Of these, 75% have been reported to be bacterial in origin whereas 20% have a fungal etiology.2 Se…
    Current Insight
    By Surendra Basti, MD; Robert M. Grohe, OD
    There is an impressive body of evidence in the recent literature that underscores the utility of scleral contact lenses for anatomic or visual rehabilitation of eyes with corneal and external ocular disease. Three groups of conditions that are otherwise difficult to treat ha…
    Current Insight
    By James V. Aquavella, MD
    This article discusses the kinds of cases for which the Rochester Eye Institute Team used the Boston KPro device, and it addresses some of the underlying reasons for the selection of this modality. This article does not report in detail on the risks, benefits, and complicati…
    Current Insight
    By Pho Nguyen, MS; Samuel C. Yiu PhD, MD
    Penetrating keratoplasty is the most common tissue transplant procedure performed in the United States, with about 35,000 cases performed each year1 and a 2-year success rate approaching 90%. The most common indications for penetrating keratoplasty (PK) are: Pseudophakic b…
    Current Insight
    By Bennie H. Jeng, MD
    Despite the possibility of endothelial rejection, full-thickness corneal transplantation is still considered the gold standard surgery for replacing a diseased cornea. Deep anterior lamellar keratoplasty (DALK) is not a new procedure, but in the past, its use has been of lim…
    Current Insight
    By Benjamin F. Mason, MD; Stephen C. Kaufman, MD, PhD; Anu Prasad, MD
    Corneal transplantation is one of the most frequently performed tissue transplantations worldwide, with an estimated 40,000 corneal transplant operations performed each year in the United States.1,2 Immunologic transplant rejection represents one of the main causes for corne…
    Current Insight
    By Sarah M. Nehls, MD
    A penetrating corneal injury or defect requires urgent medical attention and can often be effectively managed in the office by application of a tissue adhesive product. Cyanoacrylate adhesives and fibrin glues are 2 options for the management of acute corneal perforations up…
    Current Insight
    By Scott M. Guess, MD; Donald Stone, MD
    Herpetic eye disease is a common and potentially devastating manifestation of a class of viruses that include herpes simplex virus (HSV) and herpes zoster virus (HZV). Although HZV is contradistinct from HSV, the treatment of herpetic eye disease has been experiencing a slow…
    Current Insight
    By Paul P. Thompson, B Med Sc; Regis P. Kowalski, MS, M(ASCP); Evan L. Waxman, MD, PhD; Gustavo Corrales, MD; Francis S. Mah, MD
    In March, 2006, the Centers for Disease Control and Prevention (CDC) issued an alert warning of an increase in fungal keratitis eye infections nationwide that appeared to be linked to the use of Bausch & Lomb’s ReNu with MoistureLoc contact lens solution. As the CDC and othe…
    Current Insight
    By Michael A. Saidel, MD
    Early treatment of Acanthamoeba keratitis reduces long-term visual sequelae. Unfortunately, treatment of well-established Acanthamoeba keratitis remains frustrating, since diagnosis of the condition is frequently elusive. Too frequently, patients endure weeks of topical st…
    Current Insight
    By Donald Stone, MD
    With the addition of dermatologic creams for atopic disease, oral leukotriene blockers for allergic diseases, and a multitude of systemic medicines, ophthalmologists today have at their disposal a variety of therapies to safely and effectively combat ocular inflammation, whi…
    Current Insight