A 30-year-old woman presents with new onset headaches and blurry vision
Neuro-Ophthalmology/Orbit
What is your diagnosis?
The diagnosis is...

The image is consistent with optic disc edema. When this is due to increased intracranial pressure, it is called papilledema.
- Papilledema occurs when increased intracranial pressure (from any etiology) leads to optic nerve swelling.
- This can be idiopathic, due to intracranial masses or changes in cerebral spinal fluid (CSF) volume balance.
- Papilledema is usually bilateral, and swelling can be identified on fundoscopic examination.
What is the role of the primary care or emergency medicine physician?
- Perform a careful history and physical examination: evaluate risk factors, associated symptoms, and any neurologic deficits.
- Perform a direct ophthalmoscopy to check for optic disc edema.
- Refer to the emergency department (ED) immediately (or consult ophthalmology if already in the ED).
- Papilledema is an emergency: a delay in diagnosis and treatment could lead to permanent vision loss (or death, depending on the underlying cause).
What is the role of the ophthalmologist?
- Neuro-ophthalmologic imaging and evaluation to rule out other diagnoses
- Careful fundoscopic examination to categorize the severity of optic nerve swelling and track visual deficits over time
- Management and follow-up dictated by acuity
What is the treatment?
- Intracranial mass: resection, other appropriate measures
- Idiopathic: weight loss, acetazolamide, avoiding precipitating substances, managing other chronic conditions
- CSF shunting or optic nerve sheath fenestration if conservative measures unsuccessful
Learn more: Ophthalmology resources for medical students