Açaí Dye for Vitreoretinal Surgery

Dr. Mauricio Maia demonstrates the use of a novel chromovitrectomy dye based on anthocyanins from açaí fruit. This clinical video shows how the dye can be used to stain the posterior hyaloid and internal limiting membrane during vitrectomy in a human eye with a macular hole. Advantages of this dye include its heaviness, low cost and ability to concurrently stain the posterior hyaloid and ILM in a purple hue. Dr. Maia also proposes that its antioxidant properties could quench singlet oxygens that are toxic to RPE cells. Data from a phase 1 study suggests that the dye is safe for intraocular use, although long-term follow-up and additional studies will be necessary. 

Relevant Financial Disclosures: Dr. Maia holds a patent on the intraocular use of dye based on anthocyanins from the açaí fruit.