Dr. Robert Cionni shares his technique for inferior congenital coloboma repair, designed to avoid the pupil from pulling inferiorly when it constricts. He begins by separating the central and peripheral iris sphincters. Next, the central iris leaflets are sutured together using a modified Siepser knot. The remaining peripheral defects are pieced together using 3 additional suture passages, resulting in a well-centered pupil that is both functional and cosmetically pleasing.