Focal Points: Ophthalmic Features of Neurodegenerative Diseases

    This video demonstrates a patient with corticobasal ganglionic degeneration.  He shows Myerson sign, or failure to habituate the glabellar blink reflex, despite repeated glabellar tap.  He has slow, hypometric pursuit, and is unable to keep from moving his head along with his eyes. Patients with corticobasal ganglionic degeneration may develop an alien limb seemingly be out of the patient’s control.  A second patient with corticobasal ganglionic degeneration demonstrates apraxia of eyelid opening. Many such symptoms, as with benign essential blepharospasm, can be relieved by botulinum toxin.