Video Journal of Cataract & Refractive Surgery
    Cataract/Anterior Segment, Comprehensive Ophthalmology

    In this video, Dr. Minu Mathen and colleagues describe how trypan blue alters the molecular structure of the lens during cataract surgery. Using Ramen spectrometry, they discovered that trypan blue disrupts hydrogen bonds in the lens, rendering the lens less elastic. Physicians can therefore adjust the dilution and contact time of the dye to make the capsule more or less elastic. Light irradiation can reestablish some of the capsule's strength, but cannot restore the lens to its original condition.

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