JUN 14, 2010
This prospective study included 24 patients (33 eyes) with proliferative diabetic retinopathy (PDR) who either failed to respond to panretinal photocoagulation or experienced recurrence. After a single dose of bevacizumab, complete resolution occurred in 78.8 percent at one month, 63.6 percent at three months, and 45.4 percent at six months. After a second injection in the third month, the complete resolution rate increased to 60.6 percent in the sixth month. Visual acuity increased (20/225 to 20/108), macular edema decreased (11.65 mm3 to 8.92 mm3) and no complications were observed.