FEB 10, 2009
This report adds newer antiglaucoma eye drops to the list of medications that can potentially narrow and obstruct upper and lower lacrimal drainage systems. Obstruction of the lacrimal drainage system was significantly more likely among subjects in this prospective controlled blind observational case series who were taking combinations of timolol-dorzolamide or timolol-dorzolamide-pilocarpine compared with the study's control group.
Upper lacrimal drainage obstruction and any obstruction were also significantly more common among the 130 eyes of 98 patients who served as cases and were taking antiglaucoma topical medication than among controls, 280 eyes of 178 patients with no history of glaucoma who were free from ocular disease and not using topical medication.
Dr. Goldberg has no financial interests to disclose.