JUL 16, 2014
This systematic literature review found that laser-assisted subepithelial keratectomy (LASEK) and epipolis LASIK (Epi-LASIK) for myopia had similar efficacy and safety.
The authors write that although many studies have compared the relative benefits of LASEK versus Epi-LASIK in myopic patients, the results are controversial. Some indicated an advantage for either procedure, while others found no significant differences between them.
The final data analysis in this study included six studies and 517 eyes. The authors found no significant differences in efficacy, predictability, safety, epithelial healing time or corneal haze formation between the two procedures.
However, they note that follow-up was limited to one year, and the analysis included retrospective and nonrandomized studies. Furthermore, only on-flap procedures were included.
They conclude that other randomized, prospective studies with a larger sample size, identical intervention parameters, complete outcome measurements and longer follow-up are needed to increase our understanding of the benefits of LASEK over Epi-LASIK for myopic patients.