Sub-threshold micropulse diode laser photocoagulation as effective as conventional photocoagulation for DME

Researchers prospectively randomized 53 patients (84 eyes) with clinically significant diabetic macular edema to undergo one of the two photocoagulation treatments. Patients were retreated after four months as necessary. After 12 months, laser scars were found in 13.9 percent of eyes that underwent sub-threshold micropulse diode laser photocoagulation compared with 59.0 percent of conventional green laser photocoagulation-treated eyes (P < 0.001). BCVA, contrast sensitivity and retinal thickness were not significantly different between the two groups.