OCT 28, 2008
This analysis of longitudinal data from the Ocular Hypertension Study found that the rate of central corneal thickness decrease over 3.8 years is comparable to the cross-sectional age differences reported in the OHTS at the first measurement (0.6 μm/year) and comparable to other cross-sectional studies. Subgroup analyses suggest that participants treated only with topical prostaglandin analogues between the two CCT measurements had a greater rate of decrease per year than participants treated only with topical β-blockers. The authors note that the modest age- and drug-related rates of thinning they describe are unlikely to influence tonometry or clinical decision-making over the short to intermediate term.
Ophthalmology, September 2008