Topical vitamin A appears as effective as cyclosporine A for dry eye

This prospective study randomized 150 patients (300 eyes) with dry eye to one of three treatment groups:  twice daily treatment with cyclosporine A 0.05%; four times daily treatment with retinyl palmitate 0.05%, or controls, treated only with artificial tears. Participants in all three groups were given artificial tears four times a day. The vitamin A and cyclosporine groups experienced significant improvement in blurred vision, tear film BUT, Schirmer I score results and impression cytologic findings compared to controls.