Chemotherapy Injection for Retinoblastoma

Intravitreal injection of chemotherapy for retinoblastoma requires special care due to the risk of extraocular tumor extension. Dr. Lauren Dalvin demonstrates where to inject chemotherapy based on patient age, how to use an ice ball and triple freeze–thaw cryotherapy to prevent extraocular tumor spread after withdrawal, and how to distribute the medication throughout the vitreous.

Financial disclosures: Dr. Lauren Dalvin discloses financial relationships with Leonard and Mary Lou Hoeft Career Development Award Fund, National Cancer Institute, and National Center for Advancing Translational Science (Grant Support).