In this video, the presenters aim to provide a simplified, yet detailed, approach to managing corneal perforations, including preoperative assessment, choosing the right surgery, surgical tips and tricks, and nuances of postoperative care. Corneal perforations contribute significantly to the burden of corneal blindness, especially in the developing world. Their etiology can vary from infectious keratitis, being the most common, to sterile perforations secondary to neurotrophism, secondary Sjögren syndrome, peripheral ulcerative keratitis, and Mooren ulcers. Prompt diagnosis and treatment are critical as the associated ocular morbidity due to corneal perforations and their sequelae is very high. Although medical management can be used as an adjunctive measure, timely and appropriate surgical intervention forms the mainstay of treatment. The corneal surgeon has a multitude of surgical options, including tissue adhesive application, multilayered amniotic membrane grafting, Tenon patch graft, and corneal patch graft. Choosing the right option and performing it accurately are crucial to preserving anatomical and functional integrity.

Financial Disclosure: Drs. Kavya Chandran, Swapna Shanbhag, and Pravin Vaddavalli disclose no financial relationships.