FEB 23, 2022
OCTAngiolytics: A Review of Quantitative OCT Angiography Biomarkers
By
Gagan Kalra, MBBS,
Javier Zarranz-Ventura, MD, PHD,
Carolina Bernal-Morales, MD,
Marco Lupidi, MD,
Jay K Chhablani, MBBS
AAO2021 Video Program
Comprehensive Ophthalmology
With an increase in scan acquisition speeds, increased field of view and high-quality evidence proving unequivocal correlation with the established gold standard ultrawide-field fluorescein angiography, a lot of research has been conducted using optical coherence tomography angiography (OCTA) to generate quantitative vascular metrics for normal eyes and eyes with several retinal and choroidal diseases. With numerous biomarkers, methods of analysis, automated or manual or semiautomated approaches and a plethora of poorly interchangeable device-specific data described in literature, it is easy for clinicians to get overwhelmed when trying to get a holistic grasp of this topic. This video summarizes various described OCTA biomarkers, methods to achieve them and merits and challenges that come with them for analysis of chorioretinal vasculature in healthy eyes and various conditions.