The most common ocular surface neoplasia, ocular surface squamous neoplasia (OSSN), is comprised of dysplasia, carcinoma in situ, and squamous cell carcinoma. Although complete surgical excision remains the gold standard in its management, treatment modalities have evolved in the recent past. Topical chemotherapy/intralesional injections have shown promising outcomes. There is a right way of approaching any ocular tumor, including OSSN. This video reviews the various management modalities, demonstrating surgical steps, injection technique, preparation of topical medications, and clinical clues to diagnosis. The goal is to impart knowledge to specialists and comprehensive ophthalmologists to avoid misdiagnosis and accurately manage OSSN to prevent recurrence.

Financial Disclosures: Drs. Chahar and Manjandavida disclose no financial relationships.