2020–2021 BCSC Basic and Clinical Science Course™
Chapter 2: Intraocular Pressure and Aqueous Humor Dynamics
This chapter includes a related video. A link to the video is provided within the text; a page containing all videos in Section 10 is available at www.aao.org/bcscvideo_section10.
An understanding of aqueous humor dynamics is essential for the evaluation and management of glaucoma.
Aqueous humor is produced in the ciliary processes at 2–3 μL/min diurnally (and approximately 50% less nocturnally) and drains through the trabecular and uveoscleral pathways.
The parameters that contribute to intraocular pressure (IOP) are modeled by the modified Goldmann equation; they include outflow facility, aqueous humor production rate, episcleral venous pressure, and uveoscleral outflow rate.
IOP is found in the population in a skewed distribution, and glaucoma can occur at any pressure level.
Various tonometry methods can be used to estimate IOP, but all of the devices have inherent sources of measurement error.
Excerpted from BCSC 2020-2021 series: Section 10 - Glaucoma. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.