2020–2021 BCSC Basic and Clinical Science Course™
9 Uveitis and Ocular Inflammation
Chapter 15: Ocular Involvement in AIDS
Ophthalmic Manifestations
Multifocal Choroiditis and Systemic Dissemination
Multifocal choroidal lesions from a variety of infectious agents are found in up to 10% of patients with AIDS. Most of these lesions are caused by C neoformans, P jirovecii, M tuberculosis, or atypical mycobacteria. Because of the profound immunosuppression, multiple infectious agents may cause simultaneous infectious multifocal choroiditis.
The choroid is often a site of opportunistic disseminated infections and thus needs to be carefully examined in patients with AIDS. Multifocal choroiditis should prompt an exhaustive workup because it frequently is a sign of disseminated infection.
Excerpted from BCSC 2020-2021 series: Section 9 - Uveitis and Ocular Inflammation. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.