Can prednisolone eye drops make your blood pressure go up?

Most eye drops are not absorbed into the bloodstream enough to cause any significant side effects. Having said that, it is possible for topical steroid drops like prednisolone to have some mild systemic side effects such as an increase in blood sugar or blood pressure. However, this small increase on its own is usually not enough to cause these issues, unless some predisposing risks were already present.

This question was originally answered on Mar. 16, 2016.