A certain chemical can cause blood vessels that are not normal to grow under the retina. This chemical is called vascular endothelial growth factor, or VEGF. One method for treating histoplasmosis is to target VEGF.
Several anti-VEGF drugs can block the trouble-causing VEGF. Blocking VEGF reduces the growth of blood vessels and slows their leakage. This helps to slow vision loss and in some cases improves vision.
Your ophthalmologist injects the anti-VEGF drug into your eye in an outpatient procedure. Before the procedure, your ophthalmologist will clean your eye to prevent infection. They will numb your eye with anesthetic eye drops. You may receive multiple anti-VEGF injections over the course of many months. Repeat anti-VEGF treatments are often needed for continued benefit.
Laser treatment for histoplasmosis is usually done as an outpatient procedure. You will have this treatment either in the doctor’s office or at the hospital.
The laser beam in this procedure is a high-energy, focused beam of light. It produces a small burn when it hits the area of the retina where you need treatment. The burn destroys the blood vessels that are not normal. This prevents further leakage, bleeding and growth.
After laser treatment, your vision may be more blurry than before treatment. But this will often stabilize within a few weeks. A scar forms where the laser burned your retina. The scar makes a permanent blind spot that might be noticeable in your field of vision.
Laser treatment does not cure histoplasmosis. It reduces the chance of blood vessels spreading and causing more harm to your vision. If these blood vessels do return, you may need more laser surgery.
Your ophthalmologist may treat you with steroid injections. These shots in the eye reduce swelling due to histoplasmosis.
Histoplasmosis remains a threat to your vision for your lifetime. It is important to have regular checkups with your ophthalmologist to detect any problems as early as possible.